Update your browser for a better shopping experience!

Get faster load times, stronger security and access to all features.

Dramatically Different™ Moisturizing Lotion+ 50ml

Product code: T239432F

Dermatologist-developed formula that supports a stronger moisture barrier for healthier looking skin. Suitable for Very Dry and Dry Combination skin types, Dramatically Different Moisturizing Lotion+ delivers 8-hour hydration and soothing moisture for skin in need of comfort. A silky lotion that slips on easily and absorbs quickly, it helps strengthen skin’s own moisture barrier, so more moisture stays in. It also replenishes skin’s oil-water balance for healthy skin. Key ingredients include natural moisturising factors, also known as NMFs, which help pull in water and bind moisture to skin to help keep it hydrated and balanced. It's also infused with a blend of barley, sunflower and cucumber extracts. Suitable for morning and night use, apply it all over your face and neck twice daily, or wherever needed. For best results, use after Liquid Facial Soap and Clarifying Lotion. The formula is non-comedogenic, dermatologist-tested, fragrance-free and allergy-tested.

Product details

Item details

Balances skin moisture levels for moisture that lasts all day with glycerin and sodium hyaluronate that attract moisture and bind it to the skin

Strengthens skin with a potent mix of sunflower seed, barley, and cucumber extracts

More information

How to Use: Spread all over face/throat twice daily, or where needed

For best results, use after facial soap and clarifying lotion

Sunflower seed, sunflower seed cake, sunflower seed, sunflower seed cake, barley extract and cucumber fruit extract

Product Size: 50 ml

Hypoallergenic: Yes

Fragrance Free: Yes

Dermatologically Tested: Yes

Product Texture: Gel

Features

Suitable for combination skin

Suitable for oily skin

Clinique

Dramatically Different™ Moisturizing Lotion+ 50ml

£24

£4.80 per 10ml

  • Moisturising Lotion 50ml
  • 125ml
Free standard delivery over £75

Reviews (446)

4.0

59% Recommended this product

Mentions
22 June 2026Mymansgodess
Verified Purchase

Simply great

Yes, I recommend this

This is one of those products that I cannot be without. Does what I need it to do helping my complexion look calm yet vibrant and it does it gently at a cost I can afford.

Reviewer Ratings

Quality

Excellent

Helpful?

Reviewer Ratings

Quality

Excellent

14 May 2026Nicola

Changed formulation

Originally posted on Clinique UK

I have been using this moisturiser for decades but the last bottle seemed different. I persisted, then googled it and found that the recipe has changed. I don't like the feel of it - not light and fresh as it was before - and it seems to leave a plastic-feeling film on my skin. Will not be using it again.

Helpful?

16 April 2026Binacat
Verified Purchase

Works Well for Me

Yes, I recommend this

Gives my skin the right amount of coverage/elasticity without making it oily as it is well absorbed. Delivery date a bit longer than I would've liked. However worth waiting for!

Reviewer Ratings

Quality

Excellent

Helpful?

Reviewer Ratings

Quality

Excellent

07 April 2026Addingtonbelle

Brilliant stuff

Originally posted on Clinique UK

Love this amazing moisturizing lotion. Been using it for years. Try it for yourself. You won't be disappointed.

Helpful?

07 April 2026Wildflowerwendy

Daily gentle moisturiser

Originally posted on Clinique UK

I never miss using this on my aging skin. It keeps my skin soft, smooth and comfortable. I am sure it's responsible for keeping me almost wrinkle free.

Helpful?

30 March 2026Pinny

Really feels like it's protecting my skin.

Originally posted on Clinique UK

Have used dramatically different moisturiser for more years than I care to reveal and I still use it at night but felt that I ought to use something with an spf fo during the day. This is the perfect solution and really feels protective.

Helpful?

30 March 2026Spider0282

Fabulous - will never not use it

Originally posted on Clinique UK

I have been using the Clinique 3-step routine since about 1980 and I love every bit of it - especially this moisturiser, which is light, easily absorbed and makes my skin feel lovely. I will continue using it for as long as they keep making it!

Helpful?

30 March 2026Shirley P

Fab moisturising lotion

Originally posted on Clinique UK

I love love love this moisturising lotion and wouldn't buy any other. Only given 4 stars as get so frustrated with how much is left in the bottle once the pump stops working and all the faff of trying to use what is left as it's too expensive to discard.

Helpful?

16 March 2026Yvonne01
Verified Purchase

Good moisturiser

A good reputable brand and reliable moisturiser. Purchased this one for my son (so doesn't use mine up)!

Helpful?

03 March 2026Anna

So glowy!

Originally posted on Clinique UK

I use this on dry skin days, switching with moisture surge and i absoloutley love it! It does sometimes make my forehead feel a bit oily so ill probably switch to the gel or jelly next time, but the formulation is spot on :)

Helpful?

17 February 2026Rach69
Verified Purchase

Really love the feel of this product

Yes, I recommend this

I use this product regularly so bought a larger bottle for better value this time

Reviewer Ratings

Quality

Excellent

Helpful?

Reviewer Ratings

Quality

Excellent

13 February 2026Clare

Leaves skin ready for the day with or without makeup

Originally posted on Clinique UK

Have used this product for years now. Wouldn't use anything else it's light easily absorbed leaving skin ready for make up or whatever day has in store. Love it

Helpful?

13 October 2025LUCRETIA

Magically Skin Protector

Originally posted on Clinique UK

Dramatically different lotion is uniquely active to continously provide skin saving protection- we love ?? it as well as all the Clinique products all my family members use Thank you for being great ??

Helpful?

01 October 2025Poppy0344
Verified Purchase

Great product

My usual go-to product which I was able buy at a discount price .

Helpful?

30 September 2025Flowers10376

It's ok

Originally posted on Clinique UK

[This review was collected as part of a promotion.] OverallÖ it's ok. Texture is quite nice, though slightly balmy on application. No scent which I like. I just haven't noticed any difference to using my usual drugstore moisturiser which costs significantly less than this, and actually I think makes my skin look better. So it's fine, but I probably wouldn't buy it.

Helpful?

29 September 2025Clairey

Absorbs instantly

Originally posted on Clinique UK

Have been using this in the morning for a couple of months. I love the texture of this lotion and it's a perfect base for my foundation.

Helpful?

28 September 2025Mtpa

Amazing

Originally posted on Clinique UK

[This review was collected as part of a promotion.] Very good moisturiser, long lasting and perfect for my skin. Definitely order when finish

Helpful?

22 September 2025Nicki

So hydration

Originally posted on Clinique UK

[This review was collected as part of a promotion.] I absolutely love the light weight non greasy lotion, works well underneath my makeup which is a massive win for me, kept my skin so hydrated

Helpful?

20 September 2025LesleyD

Moisture heaven

Originally posted on Clinique UK

[This review was collected as part of a promotion.] I'd heard lots of good things about this moisturiser and thought that it might be too good to be true. How wrong I was! I have typical dry menopausal skin and after just a few days use, morning and night, my skin was much brighter and no dry patches. I'm just so pleased.

Helpful?

20 September 2025KittyLisa67

Loved it

Originally posted on Clinique UK

[This review was collected as part of a promotion.] Fantastic, was absorbed quickly, left my skin feeling dewy and refreshed. A little goes a long way to.

Helpful?

1 of 75